Vol. 38 No. 2, 1999
TBT (Tributyltin) Toxicity to the Visual and Olfactory Functions of Tigerperch (Terapon jarbua Forsskål)
Dar-Yi Wang and Bao-Quey Huang*
Department of Fisheries Science, National Taiwan Ocean University, Keelung, Taiwan 202
Dar-Yi Wang and Bao-Quey Huang (1999)
In order to understand tributyltin (TBT) toxicity to peripheral sensory
functions, changes of visual and olfactory structures of tigerperch (Terapon jarbua
Forsskål) were examined in juvenile and adult fish after exposure to
10, 50, and 100 µg TBT/l in juveniles and to 1 and 5 µg TBT/l in
adults, respectively, for 7 d. Severe sloughing of squamous epithelial
cells led to a thinning of the corneal epithelium. The retinomotor
response of pigmented epithelium significantly decreased from 75.33% ±
2.88% (in the control group) to 63.33% ± 4.04% (p < 0.05, n
= 3) in the 100 µg/l group. The separation and necrotic corneal
epithelium may lead to partial opacity and/or irregular abrasion and
thus decrease retinomotor responses. In addition, scanning electron
microscopic studies revealed edema, deformity, and sloughing of the
microvilli, cilia, and rods in receptor cells of the olfactory
epithelium. Electroolfactogram (EOG) responses significantly decreased
from −3.0 ± 0.6 mV to −1.3 ± 0.5 mV (1 µg/l) and −0.4 ± 0.1 (5 µg/l),
respectively (n = 3).
Key words: Tributyltin, Corneal and olfactory epithelium, Retinomotor response, Electroolfactogram (EOG).
*Correspondence: Tel: 886-2-24622192 ext. 5028. Fax: 886-2-24624790.